He worked with Mambo Graphics designing t-shirts and posters since 1986 and exhibited paintings, drawings and prints at Watters Gallery from 1975 to 2018. In 2014 Reg was made a Fellow of the National Art School in Sydney. He is now represented by Diane Larter at Roque Pop-Up Gallery. His diverse range of projects also includes taking part in solo and group art shows in Australia, New Zealand, Italy, USA, France, Britain, China and Thailand. He has had survey shows at The SH Ervin Gallery in 2007, the Manly Gallery and Museum in 2018 (with his brother Peter O'Doherty) and Ambush Gallery ANU Canberra 2019.

Reg designed several props for the closing ceremony of the Sydney Olympic Games in 2000, and in 2007 he was commissioned by Australia Post to design the "Big Things" stamp series. In 2008, as part of the Royal Australian Mint's Great Australian Artist series, a set of coins featuring Reg's iconic Kangaroo design were issued. His art appeared on another Royal Australia Mint coin in 2013 commemorating Sydney's New Year's Eve celebrations, for which he was also the official Creative Ambassador, designing a series of graphics for the event. Reg has talked and showed his work with Semi Permanent in Sydney and Brisbane in 2011, Wellington NZ in 2013 and with Ted X in 2020 in Sydney

A biography The Life and Times of Reg Mombassa' was written by Murray Waldren and published by Harper Collins in 2009. 'The Landscapes of Reg Mombassa' was published by P.Q.Blackwell in 2016. His art is included in the permanent collections of the National Gallery of Australia, National Portrait Gallery, Art Gallery of New South Wales, Powerhouse Museum, Melbourne Museum, National Art School, Macquarie University Gallery, University of Sydney Union, The British Museum, and many other significant private and institutional collections.

Sydney is a vibrant and captivating city on Australia's southeastern coast. Known for its iconic landmarks, stunning beaches, and diverse culture, Sydney offers many experiences for visitors and locals alike. The city is a melting pot of different cultures, offering a rich tapestry of cuisines, festivals, and artistic expressions.

Nestled within Sydney's eclectic mix of neighbourhoods is the charming suburb of Glebe. With its tree-lined streets and a bohemian atmosphere, Glebe is a haven for artists, students, and intellectuals. It is home to the prestigious University of Sydney, which adds an intellectual vibrancy to the area. Glebe Point Road, the suburb's main thoroughfare, is dotted with a wide array of independent bookstores, trendy cafes, and vintage shops. The lively Glebe Markets come alive on weekends, offering a treasure trove of unique crafts, fashion, and delicious street food. The suburb's proximity to the picturesque Blackwattle Bay makes it an ideal spot for leisurely walks and picnics by the water.

Just a stone's throw away from Glebe lies The Rocks, one of Sydney's oldest and most historic suburbs. The Rocks is a captivating blend of narrow laneways, sandstone buildings, and cobblestone streets. As you wander its winding paths, you can uncover the stories of Sydney's early settlers and convicts. The Rocks is also home to The Rocks Markets, where you can browse through stalls showcasing handmade jewellery, unique arts and crafts, and delicious local produce. The area's vibrant pub scene and bustling restaurants make it a popular destination for locals and tourists, offering a range of culinary delights from traditional Australian fare to international cuisines. The iconic Sydney Harbour Bridge looms majestically over The Rocks, providing a breathtaking backdrop for exploring the area.

No exploration of Sydney would be complete without mentioning its iconic landmarks, including the Sydney Opera House, and Sydney Harbour Bridge. The Sydney Opera House stands as a symbol of architectural brilliance and artistic excellence. Its distinctive sail-like design, nestled on the edge of Sydney Harbour, is instantly recognisable worldwide. The Opera House hosts a variety of performances, from opera and ballet to theatre and concerts, attracting visitors from across the globe.
Spanning the sparkling waters of Sydney Harbour, the Sydney Harbour Bridge is another emblem of the city. Often referred to as the "Coat-hanger" due to its distinctive shape, this engineering marvel offers breathtaking views of the city and the harbour. Whether you climb the bridge's arches for a thrilling adventure or admire it from a ferry cruising beneath, the Sydney Harbour Bridge leaves an indelible impression.

Sydney's allure lies not only in its iconic landmarks and breathtaking scenery but also in the unique character of its suburbs like Glebe and The Rocks. Whether you're exploring the artistic charm of Glebe or delving into the rich history of The Rocks, Sydney never fails to leave a lasting impression on all who visit.